| Some CD patients additionally suffer from Duhring's dermatitis herpetiformis, a recurrent skin disease characterized by subepidermal blisters. |
| Bullous pemphigoid is an autoimmune skin disorder characterized by subepidermal blistering that results in large, tense bullae. |
| This region passes into equally short but slightly wider second part having small subepidermal spines intruding into lumen. |
| Leukocytoclasis, endothelial swelling, and subepidermal edema are frequently noted, but vasculitis is not present. |
| It differs from other fibrous conditions such as fibromatosis, juvenile aponeurotic fibroma, subepidermal nodular fibrosis, and dermatofibrosarcoma protuberans. |
| Subjacent to this layer is a discrete subepidermal zone of parenchyma which is 3-6 cells seriate. |
