| In 3B LASER NEEDLE acupuncture applications, the special laser light triggers the release of histamine, inducing depolarization of peripheral nociceptors during therapy. |
| Pain receptors in the tissues, called the nociceptors, send electrical impulses to the brain signaling pain messages. |
| Thus, the mechanical compression of bone tissues and the algogenic substances released by the bone environment and tumor at day 8 are not sufficient to exacerbate nociceptors and stimulate abnormal neuronal firing. |
| This causes the nociceptors to generate nervous impulses, which are transmitted along the fibre into the spinal cord. |
| Technically known as 8-methyl-N-vanillyl-trans-6-nonenamide, it works by triggering nociceptors — the body's pain sensors — creating a sensation of intense heat. |
| Fish, like humans, have nociceptors which detect painful stimuli that respond to chemicals, heat and pressure. |
